Nurofen Period Pain Soft Capsules

Product Information

The white capsule-shaped tablets are marked 'N+' on one side and plain on the other. 4 Clinical Particulars If you or someone else receive too much (overdose), and experience one or more of the symptoms below, immediately and call triple zero (000) for an ambulance. Keep the person awake by talking to them or gently shaking them every now and then. You should follow the above steps even if someone other than you have accidentally used Nurofen Plus that was prescribed for you. If someone takes an overdose they may experience one or more of the following symptoms:

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A white capsule-shaped tablet, containing ibuprofen 200 mg and codeine phosphate hemihydrate 12.8 mg. Nurofen Plus may cause dizziness light-headedness or drowsiness in some people. If this occurs, do not drive or operate machinery. The use of Nurofen Plus during breastfeeding is contraindicated (also see Section 4.4 Special Warnings and Precautions for Use, CYP2D6 metabolism) due to risk of respiratory depression in the infant. Ibuprofen appears in breast milk in very low concentrations. Analgesic doses excreted in breast milk are generally low. However, infants of breastfeeding mothers taking codeine may have an increased risk of morphine overdose if the mother is an ultrarapid metabolizer of codeine. Codeine is excreted into human breast milk. Codeine is partially metabolized by cytochrome P4502D6 (CYP2D6) into morphine, which is excreted into breast milk. If nursing mothers are CYP2D6 ultra-rapid metabolisers, higher levels of morphine may be present in their breast milk. This may result in symptoms of opioid toxicity in both mother and the breastfed infant. Life-threatening adverse events or neonatal death may occur even at therapeutic doses. Do not give Nurofen Plus to children under 12 years or to those aged 12 -18 years in whom respiratory function may be compromised. Severe skin reactions. Severe skin reactions such as acute generalised exanthematous pustulosis (AGEP) has been reported in relation to ibuprofen-containing products. The acute pustular eruption may occur within the first 2 days of treatment, with fever, and numerous, small, mostly non-follicular pustules arising on a widespread oedematous erythema and mainly localised on the skin folds, trunk, and upper extremities. Patients should be carefully monitored. If signs and symptoms such as pyrexia, erythema, or many small pustules are observed, administration of Nurofen Plus should be discontinued and appropriate measures taken if needed.

6.2 Incompatibilities

Hyperalgesia. Hyperalgesia may occur with the use of opioids, particularly at high doses. Hyperalgesia may manifest as an unexplained increase in pain, increased levels of pain with increasing opioid dosages or diffuse sensitivity not associated with the original pain.

Nurofen (ibuprofen) - NetDoctor Nurofen (ibuprofen) - NetDoctor

Caution should be advised in patients receiving concomitant medications which could increase the risk of ulceration or bleeding, such as oral corticosteroids, anticoagulants such as warfarin, selective serotonin-reuptake inhibitors or anti-platelet agents such as aspirin (see Section 4.5 Interactions with Other Medicines and Other Forms of Interactions). Opioid analgesics cross the placenta. Regular use during pregnancy may cause physical dependence in the foetus, leading to withdrawal symptoms in the neonate. The use of codeine may prolong labour. Administration of codeine during labour may cause respiratory depression in the newborn infant. Nurofen Plus is contraindicated for use during the last trimester of pregnancy (see Section 4.3 Contraindications). Be careful before you drive or use any machines or tools until you know how Nurofen Plus affects you. Respiratory. Bronchospasm may be precipitated in patients suffering from, or with a history of bronchial asthma or allergic disease. Patients who have previously shown hypersensitivity reactions (e.g. asthma, rhinitis, angioedema, bronchospasm or urticaria) in response to ibuprofen, acetylsalicylic acid (aspirin) or other non-steroidal anti-inflammatory drugs (NSAIDs).

Nurofen Plus given to the mother during labour can cause breathing problems and signs of withdrawal in the newborn. Looking after your medicine

Don’t let period pain cancel your plans - Nurofen

If you take ibuprofen 3 times a day, leave at least 6 hours between doses. If you take it 4 times a day, leave at least 4 hours between doses. Opioid therapy for CNCP should be initiated as a trial in accordance with clinical guidelines and after a comprehensive biopsychosocial assessment has established a cause for the pain and the appropriateness of opioid therapy for the patient (see Hazardous and harmful use, above). The expected outcome of therapy (pain reduction rather than complete abolition of pain, improved function and quality of life) should be discussed with the patient before commencing opioid treatment, with agreement to discontinue treatment if these objectives are not met. Care is advised in the administration of Nurofen Plus to patients with adrenocortical insufficiency.These medicines may be affected by Nurofen Plus or may affect how well it works. You may need to take different amounts of your medicine, or you may need to take different medicines. Your doctor will advise you. anti-blood-clotting (anticoagulant) medicines such as warfarin, dabigatran, apixaban, rivaroxaban, heparin and low molecular weight heparins such as enoxaparin Anticholinergics. Concurrent use of codeine and anticholinergic agents may increase the risk of severe constipation and/or urinary retention. Nurofen for Children 3 months to 12 years Strawberry Suspension, Nurofen for Children 3 months to 9 years Orange Suspension, Nurofen for Children Cold, Pain and Fever 3 months to 9 years Strawberry/Orange. Contains ibuprofen. For pain and fever relief. For children from 3 months and weighing over 5kg. Nurofen for Children 100mg Chewable Capsules, Soft for children 7+ years. For pain and fever relief. For children from 7 years. Nurofen for Children Strawberry Singles 100mg/5ml Oral suspension. Contains Ibuprofen. For children over 3 months (weighing more than 5kg). For pain and fever relief. Nurofen for Children 200 mg/5 ml Orange Oral Suspension. Contains Ibuprofen. For pain and fever relief. For children from 7 years old and weighing more than 20kg. Always read the label

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This medicine is only available with a doctor's prescription. What Nurofen Plus contains Active ingredient Mifepristone. NSAIDs should not be used for 8-12 days after mifepristone administration as NSAIDs can reduce the effect of mifepristone. Continue taking your medicine for as long as your doctor tells you. If you stop having this medicine suddenly, your pain may worsen and you may experience some or all of the following withdrawal symptoms: Store it in a cool dry place where the temperature stays below 25°C away from moisture, heat or sunlight; for example, do not store it:Ibuprofen also comes as unbra Using Nurofen Plus with alcohol may result in severe drowsiness, decreased awareness, breathing difficulties, coma and death. Withdrawal Cardiovascular and cerebrovascular effects. Observational studies have indicated that NSAIDs may be associated with an increased risk of serious cardiovascular events, including myocardial infarction and stroke, which may increase with dose or duration of use. Patients with cardiovascular disease, history of atherosclerotic cardiovascular disease or cardiovascular risk factors may also be at greater risk.